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Spiraling Down The Acne
Some women are turning to non-contraceptive anti-androgen options in the treatment of their acne. Spironolactone (brand name Aldactone) is a water pill (diuretic) used to help reduce water retention in addition to helping control high blood pressure. Spironolactone has a curious molecular structure lending itself to mimic androgens. This unique architecture allows it to bind to the androgen receptor and block the true androgen from binding and triggering those undesirable “male” skin and hair traits. The downside to Spironolactone use includes symptomatic low blood pressure, irregular menstrual cycles, spotting and higher levels of potassium in the bloodstream. Avoiding excessive binging on high potassium-containing foods like bananas is important. For women who crave the benefits of an anti-androgen but want to be on oral contraceptives, or for those who want to be on a BCP but hate those extra few pounds of water retention that tend to go hand in hand, a new generation pill, Yasmin, may be a solution. Yasmin contains the progestin Drospirenone that is very similar structurally to Spironolactone. Because of its resemblance to Spironolactone, Yasmin can help avoid those extra few pounds of weight gain and may be beneficial in addressing androgenic acne. A stray pimple every month may not warrant the use of hormonal therapy. After all, the risks however small do exist. Also, the hassle may simply not be worthwhile. Women who truly suffer from androgenic acne will want to visit their physician for a complete work-up to rule out other medical conditions and to pursue an effective treatment plan. Dr Kunin board certified dermatologist DERMAdoctor.com
Bio
Dr. Kunin is a board certified dermatologist in Kansas City, Missouri. She received her dermatology training at the Medical College of Virginia. She has been featured on several local television and radio news and talk shows for her expertise in her field. She also holds a position as Associate Clinical Instructor at the University of Kansas Medical School Department of Dermatology. In addition to general dermatology, her interests in cosmetic dermatology include non-surgical approaches to skin rejuvenation, including chemical peels, Botox, Isolagen, skin care products and sclerotherapy.

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